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Bitter Orange Extract Synephrine
- fat burner
- weight loss
- citrus extract
- bitter orange
- Product description: Synephrine is natural weight loss without side effects from bitter oranges. It improves metabolic rate, available for 10%-98% HPLC.
Synephrine (or oxedrine),or more specifically, p-synephrine, is an alkaloid, extracted from citrus aurantium which is also commonly known as bitter orange, Bitter Orange, Sour Orange, and Zhi shi. p-synephrine is a primary alkaloid of Citrus aurantium extract. In another word, natural synephrine only has p-synephrine ingredient. Synephrine is commonly found in weight loss products and exercise performance.
Synephrine is a natural stimulant without side effects/positive reactions. As a fat burner, Synephrine achieves the "weight loss" results through stimulating fat dissolved,and improving metabolic rate and fat oxidation. It produces heat energy and suppresses appetite. It burns the excessive fat.
Synephrine, known as the most of active ingredient in citrus aurantium, is more and more used in weight loss products. Citrus Aurantium is a small citrus tree. Its most active components are synephrine and octopamine, but synephrine is typically in higher concentration than octopamine is. Synephrine stimulates the β-adrenergic receptors. Briefly β- receptors are located throughout the body, and four separate subtypes have been classified: β-1,β-2,β-3, and β-4 (Mutlu, Koch, and Factor, 2004). The β-3 receptors are found mostly in fat cells and are thought to be responsible for the thermogenic effects within the body. The β-1 and β-2 receptors are located mostly in the alveolar walls of the lungs. β-4 receptors seem to be a type of β-1 receptor, except they are located primarily in the myocardial cells.
Haaz et al.(2006) reviewed the available literature on synephrine for safety and efficacy. These scientists offered the judgement that although some results are promissing, larger, more well controlled trials need to be conducted before any conclusions can be drawn about the safety and efficacy of synephrine.
Synephrine fat burner
As Ephedra powder is a related substance which has been made illegal or restricted in many countries due to its use as a precursor in the illicit manufacture of the highly addictive substance, Synephrine has gained significant popularity as an alternative fat burner in drug use for weight loss.
In application of traditional Chinese medical science, it is used to dispel bloating and a lump in the abdomen and phlegm, and to cureedema, constipation, gastroptosis, prolapse of uterus and rectocele, anti tumour, prevent osteoporosis, reduce cholesterin and protect heart.
Also it is used for nerve protection and preventing diseases of degeneration of nerve, relieving menopausal symptoms of women, improving bone metabolism and protecting cardiovascular system, etc.
Bitter orange synephrine
Botanical Source: Citrus Aurantium L
CAS NO.: 94-07-5
Appearance: Yellowish brown fine powder
Assay: 98% HPLC
Apperance: white fine powder
In combination with caffeine, the Canadian Health Authority lays down a maximum daily dose of 40 mg of synephrine and 320 mg of caffeine for health adults.
Pharmaceuticals, functional food/ beverages
Synephrine for weight loss
p-Synephrine is a novel agonist for neuromedin U2 receptor, binding to NMU2R with high efficacy and potency; from which, synephrine work in body weight and energy balance regulation;
p- Synephrine increases metabolism and energy expenditure, and then achieve weight loss obviously;
p-Synephrine play as a natural fat burner and appetite suppressant;
p-Synephrine has thermogenic and lipolytic activities, increasing energy metabolism as well as athletic performance.
Synephrine improves resting metabolic rate, which is quite an important way to lose weight for obesity.
Synephrine side effects
The studies accumulated to date have not found any side effects
Xi'an ChinWon Biotech Inc., a trustworthy manufacturer, produce and supply the high purity Synephrine in long term.